Mark Stradiotto

Professor, Canada Foundation for Innovation Researcher, 2005 Dalhousie University Killam Research Prize Winner

BSc (McMaster), PhD (McMaster)

E-mail: mark.stradiotto@dal.ca
Phone: (902) 494-7190
Fax: (902) 494-1310
 
* Accepting Graduate Students 
 
Research interests: Organometallic Chemistry. 

Research efforts in the Stradiotto group are directed towards the design and construction of new organotransition metal complexes that are capable of 'activating' E-H bonds (E = main group element), including otherwise unreactive sigma-bonds (such as the C-H and C-C bonds in hydrocarbons), with the ultimate goal of incorporating such reactivity into synthetically useful stoichiometric and/or catalytic reactions. In this context, we are pursuing two main research initiatives, both of which combine fundamental and applied aspects: (a) the development of new zwitterionic (charge-neutral) catalyst complexes supported by donor-substituted indenide ligands, in anticipation that these will exhibit reactivity properties that are superior to those of more traditional cationic complexes; and (b) the design and construction of new catalyst complexes supported by planar-chiral metalloligands, for use in mediating asymmetric E-H addition reactions (e.g. hydrogenation, hydroboration, hydroamination) that are of relevance to the pharmaceutical industry. Central themes that link these programs include the establishment of new and innovative ligation strategies, the development of structure-activity relationships including mechanistic studies, and the development of entirely new and synthetically useful
metal-mediated transformations.

Visit Our lab: Stradiotto Research Group, Organometallic Synthesis and Homogeneous Catalysis